Diabetes UK Scholarship25 January 2017Dr Kathleen Gillespie, Alistair Williams and Anna Long have received £95,308 for a Diabetes UK Scholarship which will allow Claire Williams to investigate the mechanisms underlying natural regulation of the autoimmune response to Zinc Transporter 8.
Stewardship policy reduces antimicrobial use on farms
12 January 2017Evidence suggests the frequent use of certain antimicrobials (AM) in food-producing animals may reduce their effectiveness as treatments for both animals and humans. Researchers at the University of Bristol’s School of Veterinary Sciences are finding novel ways to address these concerns, working with farmers to empower them to develop policies to promote more responsible use of medicines on farms.
The new stewardship policy – facilitated by the AMR Force research group - is already informing industry and legislative bodies, allowing them to deliver real, on-farm changes while maintaining or improving herd health and welfare.
New research describes how bacteria resists ‘last-resort’ antibiotic10 January 2017An international research team, led by the University of Bristol, has provided the first clues to understand how the mcr-1 gene protects bacteria from colistin – a ‘last resort’ antibiotic used to treat life-threatening bacterial infections that do not respond to other treatment options.
Last year, members of the team, led by Dr Jim Spencer from the School of Cellular and Molecular Medicine, in collaboration with colleagues from Oxford, Cardiff, Diamond Light Source, Thailand and China, identified mcr-1 as the first colistin-resistance gene that could be passed between bacteria, enabling resistance to spread rapidly within a bacterial population.
Diabetes and Metabolism Group recognition9 January 2017Bristol's Diabetes and Metabolism Group, led by Dr Kathleen Gillespie, has been described as an exceptional training environment for postgraduate students.
NIHR award for Prof Julian Hamilton-Sheild6 January 2017Professor Julian Hamilton-Shield has lift off for an i4i NIHR study to undertake a study on "Evaluation and validation of a breath ammonia measurement technology for the improved management of patients with urea cycle defects".
Bristol researcher wins Bayer Global Ophthalmology Award14 December 2016Dr Sofia Theodoropoulou, Clinical Lecturer in Ophthalmology at Bristol, has received a Global Ophthalmology Award 2016 from Bayer. The award recognises ophthalmologists’ outstanding commitment and ambition to develop their skills and improve the lives of patients living with ophthalmic diseases.
Small droplets feel the vibe22 November 2016A team of researchers at the University of Bristol have used ultrasonic forces to accurately pattern thousands of microscopic water-based droplets. Each droplet can be designed to perform a biochemical experiment, which could pave the way for highly efficient lab-on-a-chip devices with future applications in drug discovery and clinical diagnostics.
Studies offer new insights for treating stomach infections8 November 2016Researchers have discovered a new approach to preventing or treating a stomach bacterium associated with an increased risk of stomach cancer as well as gastritis and duodenal ulcers. Writing in the journal ‘Nature Microbiology’, a team of researchers from the Technical University of Munich (TUM), the University of Duisburg-Essen at Essen University Medical Centre and the University of Bristol detail how they discovered a completely new approach to infections related to the Helicobacter pylori bacterium.
Smart stem cells home to damaged tissue28 October 2016Stem cell-based therapy promises cures for a multitude of diseases and disorders including regeneration of heart tissue, but is severely limited by the ability of stem cells to identify the damaged location and remain there after administration. A new strategy is being developed at the University of Bristol to address this challenge.
Antibiotics could be cut by up to a third, say dairy farmers26 October 2016Nine in 10 dairy farmers participating in a new survey from the Royal Association of British Dairy Farmers (RADBF) say that the farming industry must take a proactive lead in the battle against antibiotic resistance. Those questioned also think that over the next five years they could cut their own antibiotic use by almost a third in dry cow therapy and a fifth in clinical mastitis. The survey of over 300 farmers, farm managers and farm workers conducted by RADBF last month in collaboration with the University of Bristol assessed attitudes to and use of antibiotics in dairy and beef farming. It was carried out in the wake of the Government-commissioned O'Neill Review on Antimicrobial Resistance (AMR) published earlier this year.
Antimicrobial Resistance (AMR) Force25 October 2016Antimicrobial resistance (AMR) research at the School of Veterinary Sciences is promoted and facilitated by the AMR Force, who work both in the South West, nationally and internationally, and are interested in decreasing antibiotic use while improving animal health through a plurality of approaches addressing differing styles and attitudes.
Students launch new research journal25 October 2016Students from the medical and dental schools of Bristol, Cardiff, Exeter and Plymouth have joined forces to launch a new journal that showcases original research undertaken in world-class laboratories and clinics by fellow students. The ‘INSPIRE Student Health Sciences Research Journal’ is produced by a team of student editors from the four universities. It is a key part of a collaborative project under the national INSPIRE scheme funded by the Wellcome Trust and administered by the Academy of Medical Sciences.
Kidney Research UK Award24 October 2016Prof Richard Coward in the School of Clinical Sciences has been awarded a Kidney Research UK Clinical Training Fellowship.
Fund UK-China Antimicrobial Initiative Funding Success for Helen Lambert and Colleagues6 October 2016Many congratulations to Dr Helen Lambert (Social and community Medicine and the ESRC AMR Champion) and colleagues who have been awarded £882,688 (UK)/£1,828.878 (combined with NSFC funding from China) to undertake a project on "pathways to optimising antibiotic use in Anhui province: Identifying key determinants of antibiotic consumption and prescribing in community and clinical settings".
NIHR Doctoral Research Fellowship to Dr Anna Bibby28 September 2016The grant for the TILT trial is an NIHR Doctoral Research Fellowship awarded to Dr Anna Bibby to undertake a feasibility study of intra-pleural immunotherapy using the streptococcal preparation OK-432 in patients with mesothelioma.
Multiple Sclerosis Society award27 September 2016Reducing the uncertainty around MS progression is one of our top research priorities. We know that progression and increasing symptom severity is linked to the damage and loss of nerve fibres in the brain and spinal cord, but currently these are difficult to measure. This project will measure the levels of KIF proteins in the fluid surrounding the spinal cord and brain of people with MS.
Research in Bristol boosted by £21 million award over five years26 September 2016University Hospitals Bristol NHS Foundation Trust (UH Bristol) in partnership with the University of Bristol has been awarded more than £20 million over five years by the National Institute for Health Research (NIHR) to fund cutting-edge research.
Results of the Big Tick Project26 September 2016Almost one third of dogs (31 percent) checked at random during a visit to a vet were found to be carrying a tick.
Ariel Blocker Catalyst Award Success5 September 2016The Elizabeth Blackwell Institute awarded Ariel Blocker in the School of Cellular and Molecular Medicine funds from their Catalyst scheme for the pursuit of a project on "Rational vaccine design: can one identify protective antigens systematically in silico? A pilot study focusing on epitope design for Shigella and Salmonella vaccines".
Vicky Hunt Awarded an Early Career Fellowship30 August 2016Vicky Hunt in the School of Biological Sciences has been awarded an Elizabeth Blackwell Institute Early Career Fellowship in order to pursue her project "The roles of MIRNAS is parasitic nematode infection".
Prisoners and HIV Infection Rates23 August 2016A UoB team contributed to a study looking specifically at the 15 UNAIDS designated countries of Eastern Europe and Central Asia (EECA) that gained independence from the Soviet Union in 1991.
New Mechanism for Protein Secretion17 August 2016Proteins made inside the cell often need to be exported in order to do their job. A team comprised of researchers at UoB and Leeds looked at the transport motor that sits within the membrane, known as 'Sec' (for secretory).
Sexually Transmitted Infections Pitch
15 August 2016Emer Brangan gave a three minute ‘elevator pitch‘ presentation at the Society for Academic Primary Care (SAPC) conference on the CLAHRC West project looking at telephone-based management of sexually transmitted infections in primary care.
Immune Cells Remember First Meal12 August 2016Whilst an inflammatory response is beneficial for human health, many human diseases (including atheroscelerosis, cancer and arthritis) are caused or aggravated by an overzealous immune response. A greater understanding of what activates the immune response will help design novel therapies to treat these inflammatory disorders.
Support and Treatment After Replacement 9 August 2016Many knee replacement operations take place because of the pain caused by osteoarthritis. Around 20% of people will suffer moderate or severe long-term pain after their operation. Thus
roughly 15,000 people in the UK every year will have long-term pain after surgery.
Journal of Immunology Highlight9 August 2016An article published in the 15 June 2016 issue of The Journal of Immunology is being featured by the In This Issue section. The section highlights articles considered to be among the top 10% of articles published in the journal.
Amber Study25 July 2016Prof Tony Killard, Head of Biomedical Sciences at(UWE), has created a mass producible sensor which can detect ammonia levels in breath - named AmBeR.
Meeting Demand in Bacterial Factories12 July 2016Work conducted by BrisSynBio describes a new way to model productivity in bacteria used as minifactories to produce biological components. With no extra resources supplied, these bacterial ‘factories’ have to decide between making a new protein or making proteins for their own survival.