Three Minute Thesis Competition: Finals
5 May 2016
Congratulations are extended to Mr Pouya Saghedi Pour who successfully competed in the semi-finals of the 3MT and made it through to the finals.
Cardiovascular disease is the leading global cause of death, accounting for 17.3 million deaths per year, a number that is expected to grow to more than 23.6 million by 2030. At the very heart of this global problem are heart diseases initiated by heart attacks for which the damaged and necrotic heart tissue has no cure. Pouya's research, entirled Using Skin Cells to Mend Broken Hearts, conducted at the Bristol Cardiovascular and Heart Institute, is focusing on exploring the research methods in conversion of patients skin cells (fibroblasts) into cardiac cells (cardiomyocytes) through the use of the body's own cardiac transcription factors, present in the early embryo, in combination with microRNAs with the primary focus of having the converted cardiac cells being injected directly into the patient’s infarct site, thereby curing the broken heart tissue with the patient’s own cardiac cells.