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Papers in the Field of Drug Delivery:

• Barua NU, Bienemann AS, Hesketh S, Wyatt MJ, Castrique E, Love S, Gill SS. Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model. Fluids Barriers CNS. 2012 Jan 20;9(1):2.

• White E, Bienemann A, Taylor H, Hopkins K, Cameron A, Gill S. A phase I trial of carboplatin administered by convection-enhanced delivery to patients with recurrent/progressive glioblastoma multiforme. Contemp Clin Trials. 2012 Mar;33(2):320-31.

• Bienemann A, White E, Woolley M, Castrique E, Johnson DE, Wyatt M, Murray G, Taylor H, Barua N, Gill SS. The development of an implantable catheter system for chronic or intermittent convection-enhanced delivery. J Neurosci Methods. 2012 Jan 30;203(2):284-91

• White E, Bienemann A, Megraw L, Bunnun C, Wyatt M, Taylor H, Gill S. Distribution properties of lentiviral vectors administered into the striatum by convection-enhanced delivery. Hum Gene Ther. 2012 Jan;23(1):115-27

• White E, Bienemann A, Malone J, Megraw L, Bunnun C, Wyatt M, Gill S. An evaluation of the relationships between catheter design and tissue mechanics in achieving high-flow convection-enhanced delivery. J Neurosci Methods. 2011 Jul 15;199(1):87-97.

• White E, Bienemann A, Taylor H, Castrique E, Bunnun C, Wyatt M, Gill S. An evaluation of site-specific immune responses directed against first-generation adenoviral vectors administered by convection-enhanced delivery. J Gene Med. 2011 May;13(5):269-82. doi: 10.1002/jgm.1567.

• White E, Bienemann A, Megraw L, Bunnun C, Gill S. Evaluation and optimization of the administration of a selectively replicating herpes simplex viral vector to the brain by convection-enhanced delivery. Cancer Gene Ther. 2011 May;18(5):358-69.

• White E, Bienemann A, Sena-Esteves M, Taylor H, Bunnun C, Castrique E, Gill S. Evaluation and optimization of the administration of recombinant adeno-associated viral vectors (serotypes 2/1, 2/2, 2/rh8, 2/9, and 2/rh10) by convection-enhanced delivery to the striatum. Hum Gene Ther. 2011 Feb;22(2):237-51.

• White E, Woolley M, Bienemann A, Johnson DE, Wyatt M, Murray G, Taylor H, Gill SS. A robust MRI-compatible system to facilitate highly accurate stereotactic administration of therapeutic agents to targets within the brain of a large animal model. J Neurosci Methods. 2011 Jan 30;195(1):78-87.

• Patel NK, Khan S, Gill SS. Comparison of atlas- and magnetic-resonance-imaging-based stereotactic targeting of the subthalamic nucleus in the surgical treatment of Parkinson's disease. Stereotact Funct Neurosurg. 2008;86(3):153-61.

• Patel NK, Gill SS. GDNF delivery for Parkinson's disease. Acta Neurochir Suppl. 2007;97(Pt 2):135-54. Review.

• Lang AE, Gill S, Patel NK, Lozano A, Nutt JG, Penn R, Brooks DJ, Hotton G, Moro E, Heywood P, Brodsky MA, Burchiel K, Kelly P, Dalvi A, Scott B, Stacy M, Turner D, Wooten VG, Elias WJ, Laws ER, Dhawan V, Stoessl AJ, Matcham J, Coffey RJ, Traub M. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol. 2006 Mar;59(3):459-66. Erratum in: Ann Neurol. 2006 Dec;60(6):747.

• Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, Gill SS. Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med. 2005 Jul;11(7):703-4.

• Patel NK, Bunnage M, Plaha P, Svendsen CN, Heywood P, Gill SS. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study. Ann Neurol. 2005 Feb;57(2):298-302.

• Gill SS, Patel NK, Hotton GR, O'Sullivan K, McCarter R, Bunnage M, Brooks DJ, Svendsen CN, Heywood P. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med. 2003 May;9(5):589-95. Epub 2003 Mar 31.