Bristol Chemists cause a stir

PhD student Alistair Lennox

PhD student Alistair Lennox

University of Bristol chemist Professor Guy Lloyd-Jones and PhD student Alastair Lennox recently reported in the Journal of the American Chemical Society that the rate of hydrolysis of trifluoroborates, key boron reagents for the Nobel prize winning 'Suzuki-coupling' reaction, can be strongly affected by the stirring rates, and by the shape, size and material of the reaction vessel that the coupling is conducted in. Crucially, their studies also elucidate ways by which these rates can be predicted and controlled.

Professor Guy Lloyd-Jones

Professor Guy Lloyd-Jones

The impact of this work has been highlighted in the Royal Society of Chemistry publication "Chemistry World"

http://pubs.acs.org/doi/abs/10.1021/ja300236k

http://www.rsc.org/chemistryworld/News/2012/May/suzuki-reaction-organotrifluoroborate-vessel-mixing.asp