Professor John Henderson
Professor of Paediatric Respiratory Medicine
Alternative Contact: (0117) 342 8329
Telephone Number: (0117) 3310071
List of publications (links to IRIS publications database)
Current research and interests
- Genetic epidemiology of asthma and allergy in childhood. This is an ongoing programme of work based on the ALSPAC cohort. It involves collaborations with one of the largest studies of asthma genetics in the world (GABRIEL) to study asthma susceptibility genes and gene-environment interactions. There are ongoing collaborations with Imperial College (nutritional epidemiology of asthma; epigenetic studies; early life air pollution exposure and lung development), University of Manchester (collaborative research based on UK birth cohorts: the STELAR group), and the University of Birmingham (asthma and occupation)
- Social deprivation and respiratory health. A joint MRC/ESRC funded studentship (with Dept of Economics) to study the relationship between economic deprivation and respiratory ill health in childhood.
- Respiratory muscle function in progressive neuromuscular disease. This project (funded by the James Tudor Trust) is to investigate the utility of clinically applicable tools to predict the onset of respiratory failure in progressive muscle disease.
- Childhood onset of COPD. This project is being developed to study associations between irreversible pulmonary function abnormalities in adolescence as a possible precursor of chronic obstructive pulmonary disease in adulthood.
- Clinical trials. The department of respiratory medicine at Bristol Children’s Hospital is collaborating in several clinical trials (MASCOT – add-on treatment for asthma in young children; MAGNETIC – inhaled magnesium sulphate for the treatment of acute asthma) & is lead centre for TORPEDO-CF (a trial of Pseudomonas eradication in cystic fibrosis).
- Non-pharmacological treatment of asthma. John supervises an Asthma UK funded pilot study of cognitive behavioural therapy as an adjunct treatment for asthma & dysfunctional breathing.
- Member of COMP1 teaching group
- Undergraduate lectures on ‘Epidemiology of Disease in Childhood’ and ‘ Evidence-based Paediatrics’ on COMP1 course, UoB
- Supervision of postgraduate students: currently 2 MD & 1 PhD student
John is a Reader in Paediatric Respiratory Medicine. His background is in clinical paediatrics and he has trained in paediatric respiratory medicine, neonatal medicine and paediatric intensive care. His early research career was based around physiology of the respiratory system in children and infants. For the past decade, his main research interests have been centred on the epidemiology of asthma and allergy in children, working with the Avon Longitudinal Study of Parents & Children (ALSPAC). He also has a major clinical role in the assessment and treatment of children with neuromuscular diseases and has recently developed a research programme in the evaluation of respiratory muscle function in this group of young people. He has been the Deputy Editor of Archives of Disease in Childhood and is the Co-Editor of Respiratory Disorders in Forfar & Arneil’s Textbook of Pediatrics. He is currently a Co-Director of the ALSPAC study.