Heart Research UK Translational Research Grant15 December 2017Approximately 30-50% of coronary artery disease patients receiving vein bypass grafts experience re-occurrence of symptoms primarily due to excessive intimal thickening.
David Telling Grant11 December 2017Enhanced PPAR-delta expression in patients with periodontitis promotes the inflammatory and pro-atherosclerotic properties of monocytes/macrophages
The most common cause of heart attacks is atherosclerosis.
Major funding boost for internationally-recognised healthcare research centres11 December 2017Three interdisciplinary research consortia, including the University of Bristol's SPHERE project, have been allocated more than £11 million to continue healthcare sensing systems research that is revolutionising how we identify and respond to outbreaks of infectious diseases, diagnose and manage lung diseases, and recognise and solve emerging health and wellbeing issues in the home environment.
Primary care is key to optimising value in healthcare14 November 2017Balancing improvements in health against the cost of such improvements in primary care is vital to achieve a cost-effective and efficient healthcare system, finds a new report by University of Bristol researchers and published in the BMJ.
New international consortium to accelerate drug discovery in kidney diseases8 November 2017A new consortium to accelerate the discovery of novel drugs to treat kidney diseases was announced on Monday, 6 November 2017. The NEPLEX (nephron on a chip with cellular and extracellular matrix complexity) consortium, comprising leading academic institutions including the Universities of Bristol and Cambridge, and Evotec AG, will combine key technologies to develop and build a novel drug discovery device ("Nephron-on-a-Chip").
Novel pacemaker technology could transform treatment of heart failure2 November 2017Implantable devices to restore heart rhythm (eg pacemakers) are commonly used to treat heart failure and cardiovascular diseases. Groundbreaking technology, developed by academics at Bristol and Bath and supported by the EBI, promises to revolutionise the therapeutic potential of these implants.
Cost-effectiveness of screening for atrial fibrillation18 October 2017Atrial fibrillation (AF) is a major cause of stroke and mortality. Many AF patients benefit from anticoagulation therapies, which have been shown to reduce the risk of an AF-related stroke. Earlier detection could prevent AF-related strokes, disability and mortality.
Erasmus Students26 September 2017Münevver Kökçü and Ayşenur Çetinkaya from Usak University in Turkey have been awarded an Erasmus student mobility programme scholarship to spend 3 months in Professor Suleiman’s Laboratory during the period July-October 2017.
BHF Clinical Fellowship awarded26 September 2017One of our academic clinical fellows in anaesthesia, Dr Katrina Hope, has been awarded a BHF Clinical Fellowship for 3 years.
Daniel Turnberg Travel Fellowship awarded26 September 2017Dr Safa Abdul-Ghani, a former PhD Student at the University of Bristol is currently an Assistant Professor in Physiology at Al-Quds University in Jerusalem, has been awarded a Daniel Turnberg Travel Fellowship to visit Professor Suleiman’s group this summer.
New discovery could reverse tissue damage12 September 2017A new discovery by University of Bristol scientists helps to explain how cells which surround blood vessels, called pericytes, stimulate new blood vessels to grow with the hormone ‘leptin’ playing a key role. Leptin is produced by fat cells which helps to regulate energy balance in the body by inhibiting the appetite. This study, described in Scientific Reports, may have important implications for the treatment of heart attacks and also for cancer, the two main killers in the UK.
WUN Strategic Research Workshop1 August 2017The World Universities Network Global Africa Group launched its inaugural Strategic Research Workshop, hosted by the University of Ghana in a two-day event that brought together over sixty researchers from twelve WUN partner universities and ten other universities from four continents.
Transforming UK Translation commitments27 July 2017The Academy of Medical Sciences, Royal Academy of Engineering, Royal Society, and the Wellcome Trust, have outlined a series of commitments to ensure that translation is recognised and celebrated as an integral part of academic research.
Above and Beyond grant Success28 June 2017To Mustafa Zakkar, the amount of £6,249 to pursue a project entitled 'The impact of acute shear stress on venous endothelial cells inflammation and interaction with circulating white blood cells'
Queen’s birthday honour for Professor Debbie Lawlor22 June 2017Debbie Lawlor, Professor of Epidemiology at the University of Bristol, has been awarded a CBE for her services to social and community medicine research in the Queen's Birthday Honours, which recognises the achievements of a wide range of extraordinary people across the UK.
Systematic review reveals scant evidence for discontinuing medication to prevent acute kidney injury19 June 2017Kidney function can decrease suddenly when someone becomes unwell; this is more likely when the person is elderly, has other medical problems or is taking certain medicine. This drop in kidney function, acute kidney injury (AKI), can mean a higher chance of being admitted to hospital and spending longer there. One in four patients admitted to hospital with acute kidney injury do not survive. Those that do survive are often left with long term kidney damage.
Preventing progression in diabetic kidney disease13 June 2017Glitazones are drugs used to treat type 2 diabetes because they improve insulin resistance and reduce progression of associated kidney disease. But how do they work? The EBI’s Clinical Primer scheme for early-career clinicians has allowed a Bristol-based clinician, Dr Caroline Platt, to explore this question.
BHF Alumni13 June 2017The British Heart Foundation are launching a free membership programme to support their community of past and present researchers throughout the world.
Reducing heart risk from fluid overload in children on dialysis9 June 2017Teenagers on kidney dialysis have a high a risk of heart disease – as high as people 50 years older in the general population. One major problem is that there has been no reliable method of measuring fluid overload, a condition that can cause heart damage. A novel use of ultrasound could address this, and lead to more accurate dialysis prescriptions and improvements in children’s long-term cardiovascular health.
Achievements of the Chronic Kidney Disease HIT in 2016-1723 May 2017One in ten people live with chronic kidney disease (CKD). This is a long-term condition that can increase the risk of heart disease or a sudden deterioration in kidney function, also known as acute kidney injury. The Chronic Kidney Disease Health Integration Team (CKD HIT) is a team of clinical staff and patients, working together to improve patient outcomes and care pathways for patients with kidney disease.
Cost-effectiveness of BNP for heart failure25 April 2017The cost-effectiveness of B-type natriuretic peptide (BNP)- guided care is uncertain in patients with heart failure with reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF).
Mendelian randomisation in economic evaluation25 April 2017Congratulations go to Padraig Dixon on being offered not one, but two, post-doctoral fellowships. Such fellowships are important in the strong development of early career researchers. Padraig will be part of the last national cohort of MRC Skills Development Fellows before this scheme is devolved to universities.
NIHR Bristol Biomedical Research Centre: £21 million research partnership launches6 April 2017A £21 million National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) in Bristol was launched on 3 April 2017. The research centre, awarded to University Hospitals Bristol NHS Foundation Trust (UH Bristol) and the University of Bristol by the NIHR, will conduct cutting-edge research to develop new, ground-breaking treatments, diagnostics, prevention and care for patients in a wide range of diseases.
Major breakthrough in the manufacture of red blood cells28 March 2017Researchers have generated the first immortalised cell lines which allow more efficient manufacture of red blood cells. The team, from the University of Bristol and NHS Blood and Transplant, were able to manufacture red blood cells in a more efficient scale than was previously possible.
Researchers to develop ‘wearable’ robotic tools for surgery17 March 2017A collaborative team of researchers is to develop a wearable robotic system for minimally invasive surgery, also known as keyhole surgery, that will offer surgeons natural and dexterous movement as well as the ability to ‘sense’, ‘see’, control and safely navigate through the surgical environment.
Kidney Research UK grant - 214 March 2017 Awarded to Prof Moin Saleem and Dr Gavin Welsh (Co-applicant): NS and CKD Cohort/ Bio bank project – NURTuRE. Award date: 27/01/2017
Stroke Research Group
9 March 2017The Stroke Research Group is a rapidly developing independent but collaborative group of researchers. Stroke research is a priority area for growth within the Institute of Clinical Neurosciences over the coming years; the group is host to an expanding portfolio of research. The Stroke Research Group has is closely associated with the clinical stroke service at North Bristol Trust, which provides a comprehensive stroke service including interventional neuroradiology and thrombectomy, vascular surgery, neurosurgery and specialist stroke rehabilitation.