News in 2017

  • Heart Research UK Translational Research Grant 15 December 2017 Approximately 30-50% of coronary artery disease patients receiving vein bypass grafts experience re-occurrence of symptoms primarily due to excessive intimal thickening.
  • David Telling Grant 11 December 2017 Enhanced PPAR-delta expression in patients with periodontitis promotes the inflammatory and pro-atherosclerotic properties of monocytes/macrophages The most common cause of heart attacks is atherosclerosis.
  • Major funding boost for internationally-recognised healthcare research centres 11 December 2017 Three interdisciplinary research consortia, including the University of Bristol's SPHERE project, have been allocated more than £11 million to continue healthcare sensing systems research that is revolutionising how we identify and respond to outbreaks of infectious diseases, diagnose and manage lung diseases, and recognise and solve emerging health and wellbeing issues in the home environment.
  • British Heart Foundation Project Grant 28 November 2017 Attenuation of Intimal Thickening via Porcupine Inhibition grant awarded
  • British Heart Foundation Studentship Grant awarded 21 November 2017 Exploiting the inhibition of vascular smooth muscle cell proliferation and intimal thickening by PRH/HHEX
  • Primary care is key to optimising value in healthcare 14 November 2017 Balancing improvements in health against the cost of such improvements in primary care is vital to achieve a cost-effective and efficient healthcare system, finds a new report by University of Bristol researchers and published in the BMJ.
  • New international consortium to accelerate drug discovery in kidney diseases 8 November 2017 A new consortium to accelerate the discovery of novel drugs to treat kidney diseases was announced on Monday, 6 November 2017. The NEPLEX (nephron on a chip with cellular and extracellular matrix complexity) consortium, comprising leading academic institutions including the Universities of Bristol and Cambridge, and Evotec AG, will combine key technologies to develop and build a novel drug discovery device ("Nephron-on-a-Chip").
  • New Health Integration Team focusing on stroke gets go-ahead 2 November 2017 A new Health Integration Team (HIT) focused on stroke has been given the go-ahead by the Bristol Health Partners executive group.
  • Novel pacemaker technology could transform treatment of heart failure 2 November 2017 Implantable devices to restore heart rhythm (eg pacemakers) are commonly used to treat heart failure and cardiovascular diseases. Groundbreaking technology, developed by academics at Bristol and Bath and supported by the EBI, promises to revolutionise the therapeutic potential of these implants.
  • A new method for the 3D printing of living artificial tissues 1 November 2017 A team from the University of Bristol’s School of Cellular and Molecular Medicine, together with scientists at the University of Oxford, has developed a new method to 3D-print stem cells to form complex living 3D structures.
  • Risk factors for heart health linked to marital ups and downs 24 October 2017 Risk factors for heart health seem to be linked to changes over time in the quality of marital relationships — at least for men — finds a University of Bristol study published in the Journal of Epidemiology & Community Health.
  • Cost-effectiveness of screening for atrial fibrillation 18 October 2017 Atrial fibrillation (AF) is a major cause of stroke and mortality. Many AF patients benefit from anticoagulation therapies, which have been shown to reduce the risk of an AF-related stroke. Earlier detection could prevent AF-related strokes, disability and mortality.
  • Erasmus Students 26 September 2017 Münevver Kökçü and Ayşenur Çetinkaya from Usak University in Turkey have been awarded an Erasmus student mobility programme scholarship to spend 3 months in Professor Suleiman’s Laboratory during the period July-October 2017.
  • BHF Clinical Fellowship awarded 26 September 2017 One of our academic clinical fellows in anaesthesia, Dr Katrina Hope, has been awarded a BHF Clinical Fellowship for 3 years.
  • Daniel Turnberg Travel Fellowship awarded 26 September 2017 Dr Safa Abdul-Ghani, a former PhD Student at the University of Bristol is currently an Assistant Professor in Physiology at Al-Quds University in Jerusalem, has been awarded a Daniel Turnberg Travel Fellowship to visit Professor Suleiman’s group this summer.
  • New discovery could reverse tissue damage 12 September 2017 A new discovery by University of Bristol scientists helps to explain how cells which surround blood vessels, called pericytes, stimulate new blood vessels to grow with the hormone ‘leptin’ playing a key role. Leptin is produced by fat cells which helps to regulate energy balance in the body by inhibiting the appetite. This study, described in Scientific Reports, may have important implications for the treatment of heart attacks and also for cancer, the two main killers in the UK.
  • Bristol scientists to study oral bacteria that cause heart valve infection 21 August 2017 Scientists at the University of Bristol are investigating how bacteria in our mouth can cause a heart problem, called infective endocarditis. Although uncommon, infective endocarditis is a serious condition that can often be fatal.
  • WUN Strategic Research Workshop 1 August 2017 The World Universities Network Global Africa Group launched its inaugural Strategic Research Workshop, hosted by the University of Ghana in a two-day event that brought together over sixty researchers from twelve WUN partner universities and ten other universities from four continents.
  • Transforming UK Translation commitments 27 July 2017 The Academy of Medical Sciences, Royal Academy of Engineering, Royal Society, and the Wellcome Trust, have outlined a series of commitments to ensure that translation is recognised and celebrated as an integral part of academic research.
  • Above and Beyond grant Success 28 June 2017 To Mustafa Zakkar, the amount of £6,249 to pursue a project entitled 'The impact of acute shear stress on venous endothelial cells inflammation and interaction with circulating white blood cells'
  • £1.8m for major study into management of bleeding after childbirth 28 June 2017 The UK National Institute of Health Research (NIHR) has awarded a collaboration led by Liverpool, Bristol and Sunderland £1.8m to run a large study into the drug treatment of bleeding after childbirth (also called postpartum haemorrhage or PPH).
  • Queen’s birthday honour for Professor Debbie Lawlor 22 June 2017 Debbie Lawlor, Professor of Epidemiology at the University of Bristol, has been awarded a CBE for her services to social and community medicine research in the Queen's Birthday Honours, which recognises the achievements of a wide range of extraordinary people across the UK.
  • Systematic review reveals scant evidence for discontinuing medication to prevent acute kidney injury 19 June 2017 Kidney function can decrease suddenly when someone becomes unwell; this is more likely when the person is elderly, has other medical problems or is taking certain medicine. This drop in kidney function, acute kidney injury (AKI), can mean a higher chance of being admitted to hospital and spending longer there. One in four patients admitted to hospital with acute kidney injury do not survive. Those that do survive are often left with long term kidney damage.
  • Preventing progression in diabetic kidney disease 13 June 2017 Glitazones are drugs used to treat type 2 diabetes because they improve insulin resistance and reduce progression of associated kidney disease. But how do they work? The EBI’s Clinical Primer scheme for early-career clinicians has allowed a Bristol-based clinician, Dr Caroline Platt, to explore this question.
  • Informatics service support for health and biomedical research at the University of Bristol 13 June 2017 The Elizabeth Blackwell Institute for Health Research (EBI), through its Wellcome Trust ISSF Award, and match funded by the University of Bristol, invested in two posts that are openly available to help support all health and biomedical researchers across the University in their informatics needs.
  • BHF Alumni 13 June 2017 The British Heart Foundation are launching a free membership programme to support their community of past and present researchers throughout the world.
  • Reducing heart risk from fluid overload in children on dialysis 9 June 2017 Teenagers on kidney dialysis have a high a risk of heart disease – as high as people 50 years older in the general population. One major problem is that there has been no reliable method of measuring fluid overload, a condition that can cause heart damage. A novel use of ultrasound could address this, and lead to more accurate dialysis prescriptions and improvements in children’s long-term cardiovascular health.
  • Investigating the role of carotid body activation in young onset hypertension 6 June 2017 Dr Angus Nightingale has been awarded £46,612 from the David Telling Charitable Trust to pursue a project entitled "Investigating the role of carotid body activation in young onset hypertension"
  • Achievements of the Chronic Kidney Disease HIT in 2016-17 23 May 2017 One in ten people live with chronic kidney disease (CKD). This is a long-term condition that can increase the risk of heart disease or a sudden deterioration in kidney function, also known as acute kidney injury. The Chronic Kidney Disease Health Integration Team (CKD HIT) is a team of clinical staff and patients, working together to improve patient outcomes and care pathways for patients with kidney disease.
  • Bristol Universities call on students to donate rather than ditch unwanted goods 4 May 2017 The annual city-wide recycling scheme ‘Bristol Big Give’ has now begun. As end of term nears, students and city residents are urged to give any unwanted items to charity in order to reduce landfill waste and raise vital funds for charity work.
  • Cost-effectiveness of BNP for heart failure 25 April 2017 The cost-effectiveness of B-type natriuretic peptide (BNP)- guided care is uncertain in patients with heart failure with reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF).
  • Mendelian randomisation in economic evaluation 25 April 2017 Congratulations go to Padraig Dixon on being offered not one, but two, post-doctoral fellowships. Such fellowships are important in the strong development of early career researchers. Padraig will be part of the last national cohort of MRC Skills Development Fellows before this scheme is devolved to universities.
  • Bristol scientists to help heart patients by transforming veins into arteries 21 April 2017 Scientists at the University of Bristol are to investigate a new regenerative and tissue engineering technique to improve outcomes for people having heart bypass surgery.
  • NIHR Bristol Biomedical Research Centre: £21 million research partnership launches 6 April 2017 A £21 million National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) in Bristol was launched on 3 April 2017. The research centre, awarded to University Hospitals Bristol NHS Foundation Trust (UH Bristol) and the University of Bristol by the NIHR, will conduct cutting-edge research to develop new, ground-breaking treatments, diagnostics, prevention and care for patients in a wide range of diseases.
  • Major breakthrough in the manufacture of red blood cells 28 March 2017 Researchers have generated the first immortalised cell lines which allow more efficient manufacture of red blood cells. The team, from the University of Bristol and NHS Blood and Transplant, were able to manufacture red blood cells in a more efficient scale than was previously possible.
  • Stem cell therapy could help mend the youngest of broken hearts 22 March 2017 Researchers have shown stem cells from the umbilical cord may hold the key to a new generation of graft and could reduce the number of surgeries required to treat young children born with certain types of congenital heart disease.
  • Researchers to develop ‘wearable’ robotic tools for surgery 17 March 2017 A collaborative team of researchers is to develop a wearable robotic system for minimally invasive surgery, also known as keyhole surgery, that will offer surgeons natural and dexterous movement as well as the ability to ‘sense’, ‘see’, control and safely navigate through the surgical environment.
  • Kidney Research UK grant - 2 14 March 2017 Awarded to Prof Moin Saleem and Dr Gavin Welsh (Co-applicant): NS and CKD Cohort/ Bio bank project – NURTuRE. Award date: 27/01/2017
  • Kidney Research UK grant 14 March 2017 Awarded to Prof Richard Coward and Prof Craig McArdle
  • Stroke Research Group 9 March 2017 The Stroke Research Group is a rapidly developing independent but collaborative group of researchers. Stroke research is a priority area for growth within the Institute of Clinical Neurosciences over the coming years; the group is host to an expanding portfolio of research. The Stroke Research Group has is closely associated with the clinical stroke service at North Bristol Trust, which provides a comprehensive stroke service including interventional neuroradiology and thrombectomy, vascular surgery, neurosurgery and specialist stroke rehabilitation.
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