Human papilloma virus: 10 years of vaccination21 December 2018Prof Adam Finn presented at an anniversary event in Portugal celebrating 10 years of the integration of the human papilloma virus (HPV) vaccine into the country’s National Vaccination Program.
Women who are 'larks' have a lower risk of developing breast cancer6 November 2018Women who are 'larks', functioning better at the beginning of the day than the end of the day, have a lower of risk breast cancer, according to new research led by the University of Bristol presented at the 2018 NCRI Cancer Conference today [Tuesday 6 November].
Bristol to join forces with one of the world’s most prestigious research societies6 November 2018The University of Bristol partners with the Max Planck Society in Germany to establish an innovative new Max Planck Centre for Minimal Biology in Bristol. The Centre will pursue game-changing research in the emerging field of minimal biology to address some of the most complex challenges in fundamental science. This could lead to transformative applications in biotechnology and medicine.
Inflammation as a predictive tool for cancer19 October 2018Head and neck squamous cell carcinoma (HNSCC) is often associated with chronic systemic inflammation (SI). A team from the Integrative Cancer Epidemiology Programme (ICEP) assessed if DNA methylation-derived SI (mdSI) indices: Neutrophil-toLymphocyte ratio (mdNLR) and Lymphocyte-to-Monocyte ratio (mdLMR) are associated with the presence of HNSCC and overall survival (OS).
Serum calcium’s role in prostate cancer11 October 2018Prostate cancer is the most frequently diagnosed cancer among men and is a common cause of male cancer death. Global variation in mortality
and findings from migration studies provide support for a role of modifiable risk in prostate carcinogenesis.
Early detection of Cancer Conference9 October 2018Becky Richmond attended “The Early Detection of Cancer Conference” at the OHSU Knight Cancer Institute in Portland, Oregon on 2-4 October 2018.
Wellcome Board of Governors visit Bristol to hear about innovative research26 September 2018Dr Jeremy Farrar, Director of Wellcome, one of the UK’s largest research funders, visited Bristol this week [25 Sept] to meet senior staff and researchers and understand how Wellcome funding is used, explore issues of joint concern in the UK science base, and discuss future opportunities with the University.
Biomarker tool for cancer immunotherapy21 September 2018New immunotherapies which help the immune system to recognise and destroy cancer cells are promising, but some patients don’t respond to the
new treatments. With the help of an Elizabeth Blackwell Institute Clinical Primer Scheme award, Dr Emily Milodowski has been developing a new tool as a step towards being able to identify people who can be helped by these new therapies.
Treatment for diffuse intrinsic pontine glioma 20 September 2018Diffuse intrinsic pontine glioma (DIPG) is a lethal, high-grade, paediatric glioma that accounts for up to 85% of all brainstem gliomas and 100-150 new cases are recorded each year in the USA. DIPG is difficult to treat due to the heterogeneity generated from the various mutations associated with the disease, as well as its sensitive location in the brainstem. Chemotherapies have proved ineffective and new treatments are urgently required.
New network launched to enhance the rigour and reliability of UK scientific research12 September 2018A new Reproducibility Network that aims to improve the rigour and reliability of UK-led scientific research will launch at the University of Bristol this week [Wednesday 12 September]. The Network aims to reinforce the leading position of UK science by co-ordinating shared training and best practice across research-intensive universities.
Disappearing into thin air: harnessing oxygen drop could eliminate cancers without harming healthy tissue4 September 2018A major advance towards targeting cancer without harming healthy tissue has been discovered by University of Bristol researchers. The team has found a way to exploit hypoxia (reduced oxygen levels) — a condition which occurs during the development of many common cancers and drives their progression and spread. The findings, which have implications for targeted oncology, were published on 24 August 2018 in the journal EMBO Molecular Medicine.
Bristol thinking globally for health18 July 2018Rachael Gooberman-Hill, Director of Elizabeth Blackwell Institute for Health Research, University of Bristol, describes the Institute's innovative approach to global health challenges. This blog is part of the Bristol Firsts series, celebrating Bristol-based innovations in the NHS’s 70th year.
Collaborating outside of the Life Sciences6 July 2018In a recent article for Physics World, David Scott, Cancer Research UK's Director of Discovery Research and Research Communications, explores the importance of collaboration between cancer researchers and physicists and how CRUK are facilitating these important partnerships.
Cancer in the UK: State of the Nation Report6 July 2018Cancer Research UK have released their latest report summarising the current state of cancer in the UK – spanning prevention, diagnosis, treatment and survival – highlighting the progress being made as well as the challenges the UK still faces.
New evidence on link between obesity and smoking behaviour from genetic data: obese people at higher risk of smoking25 May 2018A study by the International Agency for Research on Cancer (IARC) provides new evidence that increased weight and obesity may result in increased smoking. The Cancer Research UK (CRUK)-funded study, involving University of Bristol researchers and published today in the British Medical Journal (BMJ), found that increased body mass index (BMI), body fat percentage, and waist circumference were associated both with a higher risk of being a smoker and with greater smoking intensity, measured by the number of cigarettes smoked per day. These results were consistent in both men and women.
Can a home WiFi router act as a medical sensing device?10 May 2018New research that could transform the future of healthcare will investigate whether it is possible to reuse WiFi radio waves as a medical radar system. The research, led by the University of Bristol, is part of a new £1.5 million grant awarded by the Engineering and Physical Sciences Research Council (EPSRC), Toshiba and Decawave to the OPERA project, a consortium including the universities of Bristol and Oxford; University College London and Coventry University.
EBI funded project awarded further funds to continue prehabilitation work for cancer patients9 May 2018Thanks to initial funding from University of Bristol’s Elizabeth Blackwell Institute we are now close to seeing some real impact from a prehabilitation intervention for cancer patients undergoing major surgery. The project, which aims to identify interventions that improve post-operative recovery, has been awarded further funding to take forward this important research.
New CEO of Cancer Research UK4 May 2018Michelle Mitchell OBE has been appointed as CEO of Cancer Research UK. She will replace Sir Harpal Kumar who is due to stand down in the summer.
Collaborative research to improve health and care18 April 2018Scientists are collaborating with NHS and public health staff to ensure that research evidence is used effectively to improve public health and patient outcomes. Professor Jenny Donovan, NIHR CLAHRC West Director, and Lara Edwards, NIHR CLAHRC West Manager, explain why collaboration is so important and offer some examples of the benefits it brings.
Poster Presentation on TeMMPo in Texas 1 February 2018The American Association for Cancer Research hosted the Obesity and Cancer: Mechanisms Underlying Etiology and Outcomes conference 27-30 January 2018 in Austin, Texas.