Cardiac Muscle

Ischaemia/Reperfusion Injury and Cardioprotection

  • Models of cell and whole-heart injury
  • Mitochondria
  • Ischaemic preconditioning
  • Developmental changes (neonate - adult)
  • Cell signalling pathways

Cardiac Excitation-Contraction coupling and arrythmias

  • Calcium channels, Na/Ca exchange and t-tubules
  • The Ryanodine receptor
  • Gender differences in ion channels
  • Atrial remodelling in hypertension
  • Electrophysiology of the atrio-ventricular node

Cardiac Energy Metabolism

  • Mitochondria, Ca2+ and ATP production
  • Lactate transport
  • Amino acids