Projects
- A study of abberant DNA methylation in childhood acute leukaemia and its role in the development of resistant disease
- Epigenetic and genetic lesions of the WT1 locus in AMLs.
- Flow Cytometric MRD Assessment
- Generation of functional dendritic cells from ALL patients at presentation and in remission
- Genetic polymorphism and mutation in cell signalling genes in relation to disease predisposition and treatment outcome in multiple myeloma
- Genotype and Phenotype Correlations in Acute Leukaemia.
- Minimal residual disease in treatment stratification
- Phenotypic and functional characterisation of the clonogenic population in ALL
- The assessment of immune reconstitution following transplantation and development of cellular immunotherapy
- The role of intracellular glutathione in the mechanism of glucocorticoid resistance in childhood acute lymphoblastic leukaemia
- Xenograft model of childhood acute lymphoblastic leukaemia for in vivo evaluation of targeted chemotherapeutic agents