Developmental Biology
My lab aims to understand the mechanism of embryonic development and congential disorders. We approach them at genetic, molecular, cellular, tissue and in vivo levels. We are also interested in the similarity and distinction between embryos and cancer, because they are both dynamic in gene regulation as well as in cell motility, tissue organisation and cell proliferation. The main themes of current projects are as follows:
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Hypoxia during embryogenesis
The physiological role and the effect of anti-hypoxia drugs in neural crest cell development
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Extracellular matrix
The role of extracellular matrix in non-cancerous epithelial cells and adenocarcinoma cells
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Cerebro-costo-mandibular syndrome
The impact of mutation and molecular mechanism for the phenotype
