Many assays from blood, urine and saliva are available to be explored and data has been released in the standard way - see our explore page for more details.

We also we hold a number of larger omics datasets as summarised in the table below.

Available Omics datasets

What	Who	Dataset name	Max n*	Array/Panel	Timepoint(s) [Mean age (yrs)]	N. of variants**
GENOME-WIDE DATA
Illumina 660 quad	G0 mothers	gwa_660_g0m	8654	Illumina 660 quad		467540
Illumina exome core array	G0 partners	gwa_exome_g0p	2198	Illumina exome core array		507586
Illumina 550 quad	G1	gwa_550_g1	8224	Illumina 550 quad		500527
HapMap2 imputed	G0 mothers	gi_hapmap2_g0m	8124	Illumina 550 quad + HapMap2 reference panel		2543887
	G1	gi_hapmap2_g1	8224
1000G imputed	G0 mothers	gi_1000g_g0m_g1	8654	Illumina 660 quad + HapMap2 reference pane		28699484
	G1		8797	Illumina 550 quad + 1000 genomes reference panel
	G0 partners***	gi_1000g_g0p	2198 (477 Mothers, 1721 Partners)	Illumina exome core array + 1000 genomes reference panel		27488189
HRC imputed	G0 mothers	gi_hrc_g0m_g1	8654	Illumina 660 quad + Haplotype Reference Consortium panel		41573213
	G1		8797	Illumina 550 quad + Haplotype Reference Consortium panel		41573213
CNV	G1	cnv_550_g1	7450	Illumina 550 quad		147899 unfiltered, 41628 filtered
DNA SEQUENCE DATA
Whole genome sequencing	G1	wgs_hiseq_g1	1865	Illumina HiSeq platform		44496022
Whole exome sequencing	G1	wes_novaseq_g1	3000	NOT YET AVAILABLE		NOT YET AVAILABLE
GENE EXPRESSION DATA
Gene expression	G1	ge_ht12_g1	879 (molgenis), 994 (raw), 947 (bryois)	Illumina Human HT-12 v3 bead array		48630 gene expression probe values
METHYLATION DATA
450k	G0 mothers	dnam_epic450_g0_g1 (succeeds dnam_450_g0m_g1)	962	Infinium HumanMethylation450 BeadChip	Antenatal [28.7y]	483068
			976		Focus on Mothers 1 [46.9y]	483068
	G1		905		Cord blood [Birth]	483068
			83		Children in Focus 43m [3.6y]	483068
			33		Children in Focus 61m [5.2y]	483068
			969		Focus@7 [7.5y]	483068
			361		Focus@9 [9.8y]	483068
			958		Teen focus 3/4 [17.1y]	483068
	G0 partners		554		Focus on Fathers [53.3y]	483068
EPIC	G1		1899	Infinium MethylationEPIC v1.0	Teen focus 3/4 [17.8y]	857808
			822		Focus@24 [24.4y]	857808

* subject to change due to withdrawal of consents etc

** number of variants present in released version of dataset, subject to change

*** also contains G0 mothers that were genotyped alongside the partners

 

More detailed information about these can be accessed here:  Omics Data Catalogue

In addition, the following document provides some general information on how to use ALSPAC's omics datasets: Omics data tips

 

For any queries please email: alspac-genetics@bristol.ac.uk